Endocrine Abstracts

Hyponatraemia is common in acute medical admissions, to district general hospitals presenting with neurological complications and increasing length of stay. We have carried out an audit against the following standards: full drug history; assessment of volume status; paired plasma and urinary osmolalities; appropriate fluid and Na+ management and monitoring; and target Na+>125 mmol/l on discharge.Fifty two patients with hyponatra...

Here we discuss two cases of adverse systemic effects of inhaled corticosteroids.A 38-year-old lady presented with lethargy and was noted to be cushingoid, with round face, central adiposity, and bruising. She had history of allergic rhinitis and asthma. She was receiving beclometasone both as nasal spray 100 μg b.d, and as inhaler 400 μg b.d. for the last 10 years. She had only received, a one-week course of oral steroids for acute asthma in t...

An 82-year-old lady, who was fit and well, presented with 4 days history of confusion, vomiting and slurred speech.She had recurrent cystitis, hypertension and nocturnal enuresis. She was on Adalat LA 20 mg, dosulepin 50 mg, co-amilozide 5/50 mg alternate mornings. She was started on desmopressin 0.2 mg nocte, for nocturia ten days prior to her admission.Examination showed AMTS 4/10, pulse 65/ min, blood pressure 136/66 mmHg, with ...

A 72-year-old man known to have Churg-Strauss syndrome, Type 2 diabetes mellitus, hypertension and asthma presented with history of polyuria, night sweats, weight loss of 6 kg over 8 weeks and poor mobility. Pulse rate was 88/min and blood pressure 131/74 mmHg. He had generalised muscle wasting with significant proximal myopathy and grade 4/5 power in all four limbs. There was no evidence of vasculitis, arthropathy or other neurological deficit. Blood tests showed urea 10.6 mm...